Visualizing the Heterogeneity of Tumor Vasculature
In silico simulation for cancer immunotherapy
Reversing the loss of sight.
Protein-protein interactions in peripheral arterial disease
Breast cancer metastasis in the lung: blood and lymphatic microvessels
Systems pharmacology of VEGF in cancer
Agent-based modeling of tumor growth and metastasis
Transcriptional and post-transcriptional regulation of thrombospondin-1 expression
Therapeutic peptide activates receptor Tie-2 and decreases endothelial cell permeability.
Approved HIV and rheumatoid arthritis drugs for treating breast cancer
Systems pharmacology model of cancer immune checkpoint inhibition

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Research Interests

Our laboratory focuses on applying combinations of computational modeling, bioinformatics, and in vitro and in vivo experimentation (systems biology approaches) to solve problems related to cancer,cardiovascular and ocular diseases. System biology and multiscale modeling have emerged as powerful methodologies to integrate the data from a variety of sources and at different levels of biological organization spanning multiple spatial and temporal scales. READ MORE