Selected Publications

Tumor Ensemble-Based Modeling and Visualization of Emergent Angiogenic Heterogeneity in Breast Cancer; Stamatelos SK, Bhargava A, Kim E, Popel AS, Pathak AP; Sci Rep.; 2019; Download not available
Dynamic Changes in Microvascular Flow Conductivity and Perfusion After Myocardial Infarction Shown by Image-Based Modeling; Gkontra P, El-Bouri WK, Norton KA, Santos A, Popel AS, Payne SJ, Arroyo AG; J Am Heart Assoc.; 2019; PDF
Multiscale Agent-Based and Hybrid Modeling of the Tumor Immune Microenvironment; Norton KA, Gong C, Jamalian S, Popel AS; Processes; 2019; Download not available
Mechanistic Computational Models of MicroRNA-Mediated Signaling Networks in Human Diseases; Zhao C, Zhang Y, Popel AS; Int J Mol Sci; 2019; PDF
A collagen IV-derived peptide disrupts α5β1 integrin and potentiates Ang2/Tie2 signaling; Mirando AC, Shen J, Silva RLE, Chu Z, Sass NC, Lorenc VE, Green JJ, Campochiaro PA, Popel AS, Pandey NB; JCI Insight; 2019; Download not available
Quantitative Characterization of CD8+ T Cell Clustering and Spatial Heterogeneity in Solid Tumors; Gong C, Anders RA, Zhu Q, Taube JM, Green B, Cheng W, Bartelink IH, Vicini P, Wang B, Popel AS; Front Oncol.; 2019; PDF
Three-Dimensional Transport Model for Intravitreal and Suprachoroidal Drug Injection; Zhang Y, Bazzazi H, Lima E Silva R, Pandey NB, Green JJ, Campochiaro PA, Popel AS; Invest Ophthalmol Vis Sci.; 2018; PDF
Modeling triple-negative breast cancer heterogeneity: Effects of stromal macrophages, fibroblasts and tumor vasculature; Norton KA, Jin K, Popel AS; J Theor Biol; 2018; PDF
Human expression patterns: qualitative and quantitative analysis of thrombospondin-1 under physiological and pathological conditions; Zhao C, Isenberg JS, Popel AS; J Cell Mol Med; 2018; Download not available
Biomimetic peptide display from a polymeric nanoparticle surface for targeting and antitumor activity to human triple-negative breast cancer cells; Bressler EM, Kim J, Shmueli RB, Mirando AC, Bazzazi H, Lee E, Popel AS, Pandey NB, Green JJ; J Biomed Mater Res A; 2018; Download not available
Deciphering microvascular changes after myocardial infarction through 3D fully automated image analysis; Gkontra P, Norton KA, Żak MM, Clemente C, Agüero J, Ibáñez B, Santos A, Popel AS, Arroyo AG; Sci Rep; 2018; PDF
Therapeutic potential of an anti-angiogenic multimodal biomimetic peptide in hepatocellular carcinoma; Barbhuiya MA, Mirando AC, Simons BW, Lemtiri-Chlieh G, Green JJ, Popel AS, Pandey NB, Tran PT; Oncotarget; 2018; PDF
Simultaneous blockade of IL-6 and CCL5 signaling for synergistic inhibition of triple-negative breast cancer growth and metastasis; Jin K, Pandey NB, Popel AS; Breast Cancer Res; 2018; PDF
Computational modeling of synergistic interaction between αVβ3 integrin and VEGFR2 in endothelial cells: implications for the mechanism of action of angiogenesis-modulating integrin-binding peptides; Bazzazi H, Zhang Y, Jafarnejad M, Popel AS; J Theor Biol; 2018; Download not available
Computer Simulation of TSP1 Inhibition of VEGF-Akt-eNOS: An Angiogenesis Triple Threat; Bazzazi H, Zhang Y, Jafarnejad M, Isenberg JS, Annex BH, Popel AS; Front Physiol; 2018; PDF
A computational multiscale agent-based model for simulating spatio-temporal tumour immune response to PD1 and PDL1 inhibition; Gong C, Milberg O, Wang B, Vicini P, Narwal R, Roskos L, Popel AS; J R Soc Interface; 2017; PDF
Crosstalk between stromal components and tumor cells of TNBC via secreted factors enhances tumor growth and metastasis; Jin K, Pandey NB, Popel AS; Oncotarget; 2017; PDF
An agent-based model of triple-negative breast cancer: the interplay between chemokine receptor CCR5 expression, cancer stem cells, and hypoxia; Norton KA, Wallace T, Pandey NB, Popel AS; BMC Syst Biol; 2017; PDF
Tyrosine kinase blocking collagen IV-derived peptide suppresses ocular neovascularization and vascular leakage; Silva RLE, Kanan Y, Mirando AC, Kim J, Shmueli RB, Lorenc VE, Fortmann SD, Sciamanna J, Pandey NB, Green JJ, Popel AS, Campochiaro PA; Sci Transl Med; 2017; PDF
Transcriptional and Post-Transcriptional Regulation of Thrombospondin-1 Expression: A Computational Model; Zhao C, Isenberg JS, Popel AS; PLoS Comput Biol; 2017; PDF